Clopidogrel (Plavix)
Uses/Indications
- Decrease the risk for the development of blood clots in instances of feline cardiomyopathies, pulmonary hypertension, and other causes of increased clotting risk
off label' or 'extra label'. Many drugs are commonly prescribed for off label use in veterinary medicine. In these instances, follow your veterinarian's directions and cautions very carefully as their directions may be significantly different from those on the label.
Adverse Effects
- Drooling secondary to bitter taste (more common in cats)
- Decreased appetite, vomiting or diarrhea most common side effects
- Small increased risk for bleeding
Client Information
- Best given with food to help with the taste and to avoid stomach
upset - Available in tablets. Can be reformulated in chewables. Can be made into a liquid, however not recommended due to the bitter taste
- Commonly used concurrently with aspirin
- Does not require any specific monitoring
- Please tell any veterinary professional that your pet is on Clopidogrel/Plavix, especially prior to any dental or surgical procedures
Interactions with Other Drugs
- Increased risk for bleeding if used with aspirin, coumadin, or non-steroidal antiinflammatories (Rimadyl, Deramaxx, Metacam)
- Omeprazole decreases efficacy
- Increases blood levels of torsemide
© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Created on May 24, 2019.
